San Diego Independent Scholars
November SDIS NEWSOf Mice and Men
Learning from rodent evolution about human limb development and musculoskeletal disease
A Talk by
Most of the genes required for limb development in animals are needed by both the fore and hind limbs. However, many animals have very different fore and hind limbs, and 92% of human limb birth defects specifically affect the arms or legs but not both. How are shared genes deployed differently in the two pairs of limbs? In her talk, Dr. Cooper answers this question and more by studying limb development in the mouse and its close relative, the three-toed jerboa.